Sepsis 3.0 and the Quick SOFA
Just when you thought you knew how to recognise sepsis, memorised the SIRS criteria (despite recognised shortcomings) and practice aggressive early management …
Pop Quiz! #2
Welcome to…. Pop Quiz! A series of quick-fire questions on random topics. As always, work out your answer before reading the one provided, …
Think sepsis: SIRS negative ≠ not septic
Another of the important critical care articles released by NEJM this week is this analysis on the sensitivity of the SIRS criteria …
EGDT, it had such PROMISE
The NEJM this week is overflowing with papers relevant to critical care. Amongst them is the anticipated PROMISE trial, the final chapter in …
The ARISE study released, and…
Similarly with the recently published PROCESS trial, the initial conclusion is no benefit in 90-day all-cause mortality for early goal-directed therapy. We …
What’s the ideal target for MAP in severe sepsis and septic shock?
The Surviving Sepsis Campaign recommends targeting a MAP of at least 65 mm Hg during initial resuscitation of patients with septic shock. However, …
EGDT and ProCESS
ProCESS is out. Guess what?….protocolised resus doesn’t change outcome. Worth reading this. http://www.nejm.org/doi/full/10.1056/NEJMoa1401602?query=OF A Randomized Trial of Protocol-Based Care for Early Septic …